Abstract brevetto
The invention relates to a solution comprising: a heteropolyacid and a lanthanide salt in a solvent consisting of a water/organic solvent mixture or an organic solvent. Optionally, the solution may also include an organic or inorganic buffer having a pH in the range of 4-6 or a strong base or acid. Also within the scope of the present invention is a use of said solution and any reaction products between its components as a contrastant for biological samples and a method of preparing biological samples, using said solution in at least one step, for analysis by both correlative microscopy (CLEM) and electron microscopy (EM).
Titolari
Scuola Normale Superiore di PISA, Fondazione Istituto Italiano di Tecnologia (I.I.T.)
Inventori
Valentina Cappello, Mauro GEMMI, GIOVANNI SIGNORE, Melissa SANTI, ALDO MOSCARDINI, Sebastiano DI PIETRO
Domanda di priorità
Numero deposito: IT20190001117
Data deposito: 25/01/2019
Status
Concesso
Famiglia brevettuale
Numero di deposito |
Data deposito |
Titolo |
Nazione deposito |
WO2020IB50555 |
24-01-2020 |
CONTRAST SOLUTION FOR THE CHARACTERISATION OF BIOLOGICAL SAMPLES BY ELECTRON OR CORRELATIVE MICROSCOPY |
Mondiale |
CN20208010944 |
24-01-2020 |
用于由电子显微术或关联显微术表征生物样品的造影溶液 |
Cina |
EP20200704771 |
24-01-2020 |
CONTRAST SOLUTION FOR THE CHARACTERISATION OF BIOLOGICAL SAMPLES BY ELECTRON OR CORRELATIVE MICROSCOPY |
Europeo |
US202017425699 |
24-01-2020 |
CONTRAST SOLUTION FOR THE CHARACTERISATION OF BIOLOGICAL SAMPLES BY ELECTRON OR CORRELATIVE MICROSCOPY |
Stati Uniti |
Area tematica
Sanità e Biomedicale